Living with depression can feel exhausting, isolating, and overwhelming, especially when you have been trying to cope alone for a long time. At PROMIS, our depression treatment programmes provide intensive, evidence-based support for people whose low mood is complex, long-standing, or entangled with addiction, trauma, or major life stress. With the right specialist care, meaningful and sustained recovery from depression is possible.

WHAT IS DEPRESSION TREATMENT?

Who This Treatment Is For

Depression treatment combines psychological therapy with structured clinical support to address the patterns, triggers, and underlying factors that maintain low mood. At PROMIS, treatment goes beyond symptom management — our programmes help you develop lasting strategies for emotional wellbeing, supported by an experienced multidisciplinary team.

Whether depression has developed gradually or been triggered by a specific event, PROMIS provides thorough assessment and individualised treatment planning to support your recovery.

Our approach combines evidence-based psychological therapies with psychiatric support where appropriate. Each programme is tailored to your specific needs, drawing on a range of therapeutic modalities to address the complexity of your experience.

If you are in crisis or need immediate support, contact the Samaritans on 116 123 (free, 24/7), text SHOUT to 85258, or call 999 in an emergency. You do not have to face this alone.

Who This Treatment Is For

WHO IS DEPRESSION TREATMENT FOR?

  • Feel persistently low, numb, or hopeless
  • Have tried therapy or medication without lasting relief
  • Experience depression alongside addiction or compulsive behaviours
  • Function outwardly but feel overwhelmed internally
  • Are worried about relapse or long-term patterns

Types of Depression Treatment

Effective treatment for depression typically combines structured psychological therapy with clinical support tailored to the individual. At PROMIS, we draw on approaches including CBT, DBT, interpersonal therapy, brain stimulation techniques such as rTMS and tDCS, and integrative methods to address each person’s specific needs.

Our clinical team uses structured, evidence-based psychotherapies to address both the symptoms and root causes of depression. The approaches below form part of our treatment programmes:

Cognitive Behavioural Therapy

CBT helps you understand how patterns of thinking, behaviour, and avoidance quietly maintain depression. In therapy, you’ll work collaboratively with a clinician to develop practical strategies that restore a sense of agency and momentum. Treatment usually lasts 12–20 sessions and is highly structured, making it particularly effective for people who want a clear, goal-oriented approach.

Dialectical Behaviour Therapy

DBT focuses on emotional regulation and distress tolerance — skills that are particularly helpful for people whose depression is complicated by intense emotions, impulsivity, or self-destructive patterns. You’ll learn practical techniques for managing overwhelming feelings and improving interpersonal relationships. This approach is often recommended for people with a history of trauma or when depression coexists with other difficulties.

Interpersonal Therapy (IPT)

IPT addresses how your relationships and life transitions affect your mood. This time-limited, structured approach (typically 12–16 weeks) is especially helpful when depression is triggered by grief, role changes, isolation, or conflict. You’ll work with your clinician to identify patterns in your relationships and develop healthier ways of connecting with others.

If depression is affecting your daily life, relationships, or sense of self, our team can help. PROMIS offers intensive, evidence-based depression treatment at our London and Kent clinics — including residential, day patient, and outpatient programmes. Call us on 0207 581 8222 (London) or 01304 841 700 (Kent) for a confidential conversation about your options.

What Makes Depression Treatment at PROMIS Different?

  • Integrated mental health treatment — we understand how depression and other problems often coexist
  • Senior, experienced clinicians who specialise in complex presentations
  • Trauma-informed care throughout all our programmes
  • Individualised treatment planning based on thorough assessment
  • Small client numbers ensuring personalised attention
  • Emphasis on safety, dignity, and therapeutic containment
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Medication for Depression

Medication can play an important role alongside therapy in managing depression. At PROMIS, our consultant psychiatrists carefully assess whether medication may be helpful and, if so, which approach is most appropriate for your individual circumstances. Common categories of antidepressant medication include:

Selective Serotonin Reuptake Inhibitors (SSRIs)

SSRIs are among the most commonly prescribed antidepressants and work by increasing serotonin availability in the brain. They are often recommended as a first-line option because they tend to be well-tolerated. Our psychiatrists will discuss whether an SSRI may be appropriate for you, and will monitor your response carefully throughout treatment.

Norepinephrine and Dopamine Reuptake Inhibitors

NDRIs work by increasing the availability of norepinephrine and dopamine in the brain, which can help improve mood, energy, and concentration. They may be considered when SSRIs are not suitable or have not been effective.

Monoamine Oxidase Inhibitors

MAOIs are an established class of antidepressant that may be considered when other medications have not been effective. They work by preventing the breakdown of key mood-regulating neurotransmitters in the brain.